Cat. No.: IBDA-434777
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Online InquiryTarget Information
| Target Name | ICAM1 |
| Uniprot ID | P05362 |
| Cellular Localization | Membrane. |
| Immunogen | Synthetic peptide within Human ICAM1 aa 1-100 (N terminal). |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Product Details
| Description | Rabbit monoclonal antibody to ICAM1. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide within Human ICAM1 aa 1-100 (N terminal). |
| Positive Control | WB: Huvec, Ramos and Raji whole cell lysate. IHC: Human kidney and tonsil tissue. |
| Application | IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |