Cat. No.: IBDA-434776
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Online InquiryTarget Information
| Target Name | ICAM1 |
| Uniprot ID | P05362 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant fragment within Human ICAM1 aa 300-500 (C terminal). |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Product Details
| Description | Rabbit monoclonal antibody to ICAM1. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment within Human ICAM1 aa 300-500 (C terminal). |
| Positive Control | IHC-P: Human lung carcinoma and tonsil tissue sections. Flow Cyt (Intra): Ramos cells. ICC/IF: Raji cells. IP: Raji whole cell lysate. WB: HUVEC treated with 10ng/ml for 18 hours and Ramos whole cell lysate. |
| Application | Flo, ICC/IF, IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 0.05% BSA, 40% Glycerol, 59% PBS |
| Handling | Avoid freeze-thaw cycles. |