Cat. No.: IBDA-434754
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Online InquiryTarget Information
| Target Name | ICAM1 |
| Uniprot ID | P05362 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant fragment within Human ICAM1 aa 300-500 (C terminal). |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Product Details
| Description | Rabbit monoclonal antibody to ICAM1. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Alexa Fluor® 488 |
| Reactivity | Human |
| Immunogen | Recombinant fragment within Human ICAM1 aa 300-500 (C terminal). |
| Positive Control | ICC/IF: Raji cells |
| Application | ICC/IF |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C. Store in the dark |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 30% Glycerol, 1% BSA, PBS |
| Handling | Avoid freeze-thaw cycles. |