IKB Alpha Monoclonal Antibody - BSA and Azide Free

Target Information

Target Name	IKB Alpha
Uniprot ID	P25963
Cellular Localization	Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Immunogen	Recombinant fragment.
Function	Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Product Details

Description	Rabbit monoclonal antibody to IKB alpha - BSA and Azide Free (Detector).
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse
Immunogen	Recombinant fragment.
Application	sELISA

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	Constituent: 100% PBS