IKB Beta Monoclonal Antibody - BSA and Azide Free

Target Information

Target Name	IKB Beta
Uniprot ID	Q15653
Cellular Localization	Cytoplasm. Nucleus.
Immunogen	Synthetic peptide.
Function	Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Product Details

Description	Rabbit monoclonal antibody to IKB beta - BSA and Azide Free.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide.
Positive Control	WB: Jurkat, HeLa, THP-1, and MCF7 cell lysates. IP: HeLa cells. IHC-P: Human kidney tissue. ICC/IF: Jurkat cells. Flow Cyt (Intra): Jurkat cells.
Application	Flo, ICC/IF, IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 7.2 Constituent: PBS
Handling	Do not freeze.