Cat. No.: IBDA-431844
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Online InquiryTarget Information
| Target Name | IKB Beta (phospho S23) |
| Uniprot ID | Q15653 |
| Cellular Localization | Cytoplasm. Nucleus. |
| Immunogen | Synthetic peptide corresponding to Human IKB beta (phospho S23). |
| Function | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. |
Product Details
| Description | Rabbit polyclonal antibody to IKB beta (phospho S23). |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to Human IKB beta (phospho S23). |
| Positive Control | Human breast carcinoma tissue. |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 0.87% Sodium Chloride, 50% Glycerol, PBS Without Mg2+ and Ca2+ |
| Handling | Avoid freeze-thaw cycles. |