Cat. No.: IBDA-431843
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Online InquiryTarget Information
| Target Name | IKB Beta |
| Uniprot ID | Q15653 |
| Cellular Localization | Cytoplasm. Nucleus. |
| Immunogen | Synthetic peptide within Human IKB beta aa 306-356. |
| Function | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. |
Product Details
| Description | Rabbit polyclonal antibody to IKB beta. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide within Human IKB beta aa 306-356. |
| Positive Control | WB: HeLa and HEK-293T whole cell lysates. IP: HeLa whole cell lysate. |
| Application | IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 6.8 Preservative: 0.09% Sodium Azide Constituent: Tris Buffered Saline, 0.1% BSA |
| Handling | Avoid freeze-thaw cycles. |