Cat. No.: IBDA-435279
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Online InquiryTarget Information
| Target Name | IKK Beta |
| Uniprot ID | O14920 |
| Cellular Localization | Cytoplasm. Membrane raft. Colocalized with DPP4 in membrane rafts. |
| Immunogen | Synthetic peptide within Human IKK beta aa 650-750 (C terminal). |
| Function | Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3. |
Product Details
| Description | Rabbit monoclonal antibody to IKK beta. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Human |
| Immunogen | Synthetic peptide within Human IKK beta aa 650-750 (C terminal). |
| Positive Control | WB: Wild-type HAP1 cell lysate. HeLa, NIH/3T3 and Daudi cell lysate. IHC-P: Human cervical carcinoma tissue. IP: SH-SY5Y whole cell lysate. |
| Application | IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |