Cat. No.: IBDA-435275
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Online InquiryTarget Information
| Target Name | IKK Beta (phospho Y188) |
| Uniprot ID | O14920 |
| Cellular Localization | Cytoplasm. Membrane raft. Colocalized with DPP4 in membrane rafts. |
| Immunogen | Synthetic peptide corresponding to Human IKK beta aa 150-250 (phospho Y188). |
| Function | Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3. |
Product Details
| Description | Rabbit polyclonal antibody to IKK beta (phospho Y188). |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to Human IKK beta aa 150-250 (phospho Y188). |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 50% Glycerol, 0.87% Sodium Chloride, PBS |
| Handling | Avoid freeze-thaw cycles. |