Cat. No.: IBDA-435272
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Online InquiryTarget Information
| Target Name | IKK Beta |
| Uniprot ID | O14920 |
| Cellular Localization | Cytoplasm. Membrane raft. Colocalized with DPP4 in membrane rafts. |
| Immunogen | Recombinant fragment within Human IKK beta aa 185-448. |
| Function | Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3. |
Product Details
| Description | Rabbit polyclonal antibody to IKK beta. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment within Human IKK beta aa 185-448. |
| Positive Control | Jurkat, Raji, K562, THP1 and NCI-H929 whole cell lysates. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7 Preservative: 0.01% Thimerosal (Merthiolate) Constituent: 1.21% Tris, 0.75% Glycine, 10% Glycerol |
| Handling | Avoid freeze-thaw cycles. |