Cat. No.: IBDA-435271
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Online InquiryTarget Information
Target Name | IKK Beta |
Uniprot ID | O14920 |
Cellular Localization | Cytoplasm. Membrane raft. Colocalized with DPP4 in membrane rafts. |
Immunogen | Recombinant fragment corresponding to amino acids 493-709 of Human IKK beta. |
Function | Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3. |
Product Details
Description | Rabbit polyclonal antibody to IKK beta. |
Host Species | Rabbit |
Clonality | Polyclonal |
Purity | Immunogen affinity purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant fragment corresponding to amino acids 493-709 of Human IKK beta. |
Positive Control | 293T, A431 and H1299 whole cell lysates |
Application | ICC/IF, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Upon delivery aliquot. Store at -20 °C or -80 °C |
Storage Buffer | pH: 7 Preservative: 0.01% Thimerosal (Merthiolate) Constituent: 1.21% Tris, 0.75% Glycine, 10% Glycerol |
Handling | Avoid freeze-thaw cycles. |