Cat. No.: IBDA-431170
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Online InquiryTarget Information
| Target Name | IKK Gamma/NEMO |
| Uniprot ID | Q9Y6K9 |
| Cellular Localization | Cytoplasm. Nucleus. Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress. |
| Immunogen | Recombinant full length protein. |
| Function | Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity (By similarity). Essential for viral activation of IRF3. |
Product Details
| Description | Rabbit monoclonal antibody to IKK gamma/NEMO - BSA and Azide Free. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat, Human |
| Immunogen | Recombinant full length protein. |
| Positive Control | WB: Human fetal brain, Human fetal kidney, Human colon cancer, HEK293 whole cell lysates, HeLa whole cell lysates, K562 whole cell lysates, Jurkat whole cell lysates. Mouse brain, heart, kidney and spleen. Rat brain, heart, kidney and spleen. C6 whole cell lysates, RAW 264.7 whole cell lysates, PC-12 whole cell lysates, NIH/3T3 whole cell lysates. IHC-P: Human colonic adenocarcinoma, rat colon. ICC/IF: HeLa, NIH/3T3 |
| Application | ICC/IF, IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.2 Constituent: PBS |
| Handling | Do not freeze. |