Cat. No.: IBDA-431174
Size:
Online InquiryTarget Information
| Target Name | IKK Gamma/NEMO |
| Uniprot ID | Q9Y6K9 |
| Cellular Localization | Cytoplasm. Nucleus. Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress. |
| Immunogen | Recombinant fragment. |
| Function | Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity (By similarity). Essential for viral activation of IRF3. |
Product Details
| Description | Rabbit monoclonal antibody to IKK gamma/NEMO - BSA and Azide Free. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment. |
| Positive Control | WB: HEK293T cell lysate. |
| Application | ICC/IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.2 Constituent: PBS |
| Handling | Do not freeze. |