Cat. No.: IBDA-431173
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Online InquiryTarget Information
Target Name | IKK Gamma/NEMO |
Uniprot ID | Q9Y6K9 |
Cellular Localization | Cytoplasm. Nucleus. Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress. |
Function | Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity (By similarity). Essential for viral activation of IRF3. |
Product Details
Description | Rabbit monoclonal antibody to IKK gamma/NEMO - BSA and Azide Free (Detector). |
Host Species | Rabbit |
Clonality | Monoclonal |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Application | sELISA |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | Constituent: 100% PBS |