IKK Gamma/NEMO Monoclonal Antibody

Target Information

Target Name	IKK Gamma/NEMO
Uniprot ID	Q9Y6K9
Cellular Localization	Cytoplasm. Nucleus. Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress.
Immunogen	Recombinant full length protein corresponding to Human IKK gamma/NEMO aa 1 to the C-terminus.
Function	Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity (By similarity). Essential for viral activation of IRF3.

Product Details

Description	Rabbit monoclonal antibody to IKK gamma/NEMO.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Alexa Fluor® 647
Reactivity	Human
Immunogen	Recombinant full length protein corresponding to Human IKK gamma/NEMO aa 1 to the C-terminus.
Positive Control	ICC/IF: HeLa cells
Application	ICC/IF

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C. Store in the dark
Storage Buffer	pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 1% BSA, 30% Glycerol, PBS
Handling	Avoid freeze-thaw cycles.