Cat. No.: IBDA-431169
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Online InquiryTarget Information
| Target Name | IKK Gamma/NEMO (phospho S85) |
| Uniprot ID | Q9Y6K9 |
| Cellular Localization | Cytoplasm. Nucleus. Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress. |
| Immunogen | Synthetic peptide corresponding to Human IKK gamma/NEMO (phospho S85). |
| Function | Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity (By similarity). Essential for viral activation of IRF3. |
Product Details
| Description | Rabbit polyclonal antibody to IKK gamma/NEMO (phospho S85). |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to Human IKK gamma/NEMO (phospho S85). |
| Positive Control | Extracts from HepG2 cells |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: PBS, 50% Glycerol, 0.87% Sodium Chloride Without Mg2+ and Ca2+ |
| Handling | Avoid freeze-thaw cycles. |