IKK Gamma/NEMO Polyclonal Antibody

Target Information

Target Name	IKK Gamma/NEMO
Uniprot ID	Q9Y6K9
Cellular Localization	Cytoplasm. Nucleus. Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress.
Immunogen	Recombinant fragment corresponding to Human IKK gamma/NEMO aa 1-150.
Function	Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity (By similarity). Essential for viral activation of IRF3.

Product Details

Description	Rabbit polyclonal antibody to IKK gamma/NEMO.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Rat, Human
Immunogen	Recombinant fragment corresponding to Human IKK gamma/NEMO aa 1-150.
Positive Control	WB: HepG2, NIH/3T3 and NBT-II cell lysate. ICC/IF: U-251 MG cells. IHC-P: Human placenta tissue.
Application	ICC/IF, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.20 Preservative: 0.02% Sodium Azide Constituent: PBS, 40% Glycerol
Handling	Avoid freeze-thaw cycles.