Cat. No.: IBDA-431168
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Online InquiryTarget Information
| Target Name | IKK Gamma/NEMO |
| Uniprot ID | Q9Y6K9 |
| Cellular Localization | Cytoplasm. Nucleus. Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress. |
| Immunogen | Recombinant fragment corresponding to Human IKK gamma/NEMO aa 1-150. |
| Function | Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity (By similarity). Essential for viral activation of IRF3. |
Product Details
| Description | Rabbit polyclonal antibody to IKK gamma/NEMO. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat, Human |
| Immunogen | Recombinant fragment corresponding to Human IKK gamma/NEMO aa 1-150. |
| Positive Control | WB: HepG2, NIH/3T3 and NBT-II cell lysate. ICC/IF: U-251 MG cells. IHC-P: Human placenta tissue. |
| Application | ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.02% Sodium Azide Constituent: PBS, 40% Glycerol |
| Handling | Avoid freeze-thaw cycles. |