IKKi/IKKe Monoclonal Antibody

Target Information

Target Name	IKKi/IKKe
Uniprot ID	Q14164
Cellular Localization	Cytoplasm. Nucleus. Nucleus > PML body. Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent.
Immunogen	Recombinant fragment corresponding to Human IKKi/IKKe aa 1-250 (N terminal).
Function	Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death.

Product Details

Description	Mouse monoclonal antibody to IKKi/IKKe - N-terminal.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG2a
Conjugation	Unconjugated
Reactivity	Mouse, Human
Immunogen	Recombinant fragment corresponding to Human IKKi/IKKe aa 1-250 (N terminal).
Positive Control	Jurkat, HepG2 and mouse NIH 3T3 cell lysates. Human thyroid cancer tissue.
Application	IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	Preservative: 0.05% Sodium Azide Constituent: 99% PBS, 0.05% BSA
Handling	Avoid freeze-thaw cycles.