Cat. No.: IBDA-431940
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Online InquiryTarget Information
Target Name | IKKi/IKKe |
Uniprot ID | Q14164 |
Cellular Localization | Cytoplasm. Nucleus. Nucleus > PML body. Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent. |
Immunogen | Synthetic peptide within Human IKKi/IKKe aa 1-100. |
Function | Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death. |
Product Details
Description | Rabbit monoclonal antibody to IKKi/IKKe. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Synthetic peptide within Human IKKi/IKKe aa 1-100. |
Positive Control | HeLa, Raji, MCF7 and Jurkat whole cell lysate. Human tonsil tissue. |
Application | Flo, IHC-P, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at -20 °C |
Storage Buffer | pH: 7.20 Preservative: 0.05% Sodium Azide Constituent: 0.1% BSA, 40% Glycerol, 9.85% Tris Glycine, 50% Tissue Culture Supernatant |
Handling | Avoid freeze-thaw cycles. |