Cat. No.: IBDA-431940
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Online InquiryTarget Information
| Target Name | IKKi/IKKe |
| Uniprot ID | Q14164 |
| Cellular Localization | Cytoplasm. Nucleus. Nucleus > PML body. Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent. |
| Immunogen | Synthetic peptide within Human IKKi/IKKe aa 1-100. |
| Function | Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death. |
Product Details
| Description | Rabbit monoclonal antibody to IKKi/IKKe. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide within Human IKKi/IKKe aa 1-100. |
| Positive Control | HeLa, Raji, MCF7 and Jurkat whole cell lysate. Human tonsil tissue. |
| Application | Flo, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.05% Sodium Azide Constituent: 0.1% BSA, 40% Glycerol, 9.85% Tris Glycine, 50% Tissue Culture Supernatant |
| Handling | Avoid freeze-thaw cycles. |