Cat. No.: IBDA-435088
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Online InquiryTarget Information
| Target Name | IL-1 Alpha |
| Uniprot ID | P01583 |
| Cellular Localization | Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
| Immunogen | Recombinant full length protein corresponding to Human IL-1 alpha aa 100 to the C-terminus. |
| Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
Product Details
| Description | Mouse monoclonal antibody to IL-1 alpha. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A/G purified |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Reactivity | Rat, Human |
| Immunogen | Recombinant full length protein corresponding to Human IL-1 alpha aa 100 to the C-terminus. |
| Positive Control | IHC-P: Human kidney, prostate, stomach cancer and stomach tissue. WB: Recombinant human IL-1 alpha protein. Rat liver lysate. |
| Application | IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: PBS, 50% Glycerol |
| Handling | Avoid freeze-thaw cycles. |