Cat. No.: IBDA-431781
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Online InquiryTarget Information
| Target Name | IL-23R |
| Uniprot ID | Q5VWK5 |
| Cellular Localization | Cell membrane. |
| Immunogen | Recombinant fragment corresponding to Human IL-23R aa 250-450. |
| Function | Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. |
Product Details
| Description | Mouse monoclonal antibody to IL-23R. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein G purified |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment corresponding to Human IL-23R aa 250-450. |
| Positive Control | WB: MCF7, THP-1 and A431 cell lysates. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | Preservative: 0.05% Sodium Azide Constituent: PBS, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |