Cat. No.: IBDA-431780
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Online InquiryTarget Information
Target Name | IL-23R |
Uniprot ID | Q5VWK5 |
Cellular Localization | Cell membrane. |
Immunogen | Recombinant full length protein corresponding to Human IL-23R. |
Function | Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. |
Product Details
Description | Rabbit polyclonal antibody to IL-23R. |
Host Species | Rabbit |
Clonality | Polyclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Mouse, Rat, Human |
Immunogen | Recombinant full length protein corresponding to Human IL-23R. |
Positive Control | Extracts of K562 cell lines. |
Application | ICC/IF, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | pH: 7.30 Preservative: 0.02% Sodium Azide Constituent: 50% Glycerol, 49% PBS |
Handling | Avoid freeze-thaw cycles. |