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IL37 Monoclonal Antibody - BSA and Azide Free

Cat. No.: IBDA-431320

Size:

Target Information

Target Name IL37
Uniprot ID Q9NZH6
Cellular Localization Cytoplasm > cytosol. Nucleus. Secreted. Stimulation with IL1B leads to colocalization with SMAD3 mostly in perinuclear regions. Only the CASP1-cleaved mature form translocates into the nucleus upon LPS stimulation.
Function Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

Product Details

Description Rabbit monoclonal antibody to IL37 - BSA and Azide Free (Detector).
Host Species Rabbit
Clonality Monoclonal
Isotype IgG
Conjugation Unconjugated
Reactivity Human
Application sELISA

Storage & Handling

Shipping Shipped at 4 °C.
Storage Store at 4 °C
Storage Buffer Constituent: 100% PBS
! For research use only, not intended for any clinical use.
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