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Integrin Alpha 4/CD49D Monoclonal Antibody

Cat. No.: IBDA-434013

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Target Information

Target Name Integrin Alpha 4/CD49D
Uniprot ID P13612
Cellular Localization Membrane.
Immunogen The details of the immunogen for this antibody are not available.
Function Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

Product Details

Description APC Mouse monoclonal antibody to Integrin alpha 4/CD49D.
Host Species Mouse
Clonality Monoclonal
Purity Size exclusion
Isotype IgG1
Conjugation APC/Cy7®
Reactivity Human
Immunogen The details of the immunogen for this antibody are not available.
Positive Control Flow Cyt: Human peripheral whole blood.
Application Flo

Storage & Handling

Shipping Shipped at 4 °C.
Storage Store at 4 °C. Store in the dark
Storage Buffer pH: 7.4
Preservative: 0.0975% Sodium Azide
Constituent: PBS
! For research use only, not intended for any clinical use.