Cat. No.: IBDA-434013
Size:
Online InquiryTarget Information
Target Name | Integrin Alpha 4/CD49D |
Uniprot ID | P13612 |
Cellular Localization | Membrane. |
Immunogen | The details of the immunogen for this antibody are not available. |
Function | Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. |
Product Details
Description | APC Mouse monoclonal antibody to Integrin alpha 4/CD49D. |
Host Species | Mouse |
Clonality | Monoclonal |
Purity | Size exclusion |
Isotype | IgG1 |
Conjugation | APC/Cy7® |
Reactivity | Human |
Immunogen | The details of the immunogen for this antibody are not available. |
Positive Control | Flow Cyt: Human peripheral whole blood. |
Application | Flo |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C. Store in the dark |
Storage Buffer | pH: 7.4 Preservative: 0.0975% Sodium Azide Constituent: PBS |