Cat. No.: IBDA-434017
Size:
Online InquiryTarget Information
| Target Name | Integrin Alpha 4/CD49D |
| Uniprot ID | P13612 |
| Cellular Localization | Membrane. |
| Immunogen | Synthetic peptide within Human Integrin alpha 4/CD49D aa 982-1032. |
| Function | Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. |
Product Details
| Description | Rabbit polyclonal antibody to Integrin alpha 4/CD49D. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide within Human Integrin alpha 4/CD49D aa 982-1032. |
| Positive Control | WB: Jurkat whole cell lysate. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7 Preservative: 0.09% Sodium Azide Constituent: Tris Citrate/Phosphate |
| Handling | Avoid freeze-thaw cycles. |