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INY-03-041 trihydrochloride

Cat. No.: IBDI-435033

INY-03-041 trihydrochloride is a potent, highly selective and PROTAC-based pan-AKT degrader consisting of the ATP-competitive AKT inhibitor Ipatasertib (HY-15186) conjugated to Lenalidomide (HY-A0003, Cereblon ligand). INY-03-041 trihydrochloride inhibits AKT1, AKT2 and AKT3 with IC50s of 2.0, 6.8 and 3.5 nM, respectively.

Size (Solid):

Product Details

Target PROTACs | Akt
Molecular Weight 907.80
Appearance Solid
SMILES O=C(C(N(CC1=C2C=CC=C1CCCCCCCCCCNC[[email protected]](C3=CC=C(Cl)C=C3)C(N4CCN(C5=C([[email protected]](C)C[[email protected]]6O)C6=NC=N5)CC4)=O)C2=O)CC7)NC7=O.Cl.Cl.Cl
Purity 99.27%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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