Cat. No.: IBDA-435480
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Online InquiryTarget Information
| Target Name | IRAK-1 (phospho T209) |
| Immunogen | Synthetic peptide within Mouse IRAK-1 aa 150-250 (phospho T209) conjugated to keyhole limpet haemocyanin. |
| Function | Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Isoform 1 binds rapidly but is then degraded allowing isoform 2 to mediate a slower, more sustained response to the cytokine. Isoform 2 is inactive suggesting that the kinase activity of this enzyme is not required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1. |
Product Details
| Description | Rabbit polyclonal antibody to IRAK-1 (phospho T209). |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse |
| Immunogen | Synthetic peptide within Mouse IRAK-1 aa 150-250 (phospho T209) conjugated to keyhole limpet haemocyanin. |
| Positive Control | IHC-P: Mouse placenta tissue. |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.09% Sodium Azide Constituent: 1% BSA, 50% Glycerol |
| Handling | Avoid freeze-thaw cycles. |