IRAK4-IN-15

Cat. No.: IBDI-433035

IRAK4-IN-15 (compound 35) is a potent and selective IRAK4 inhibitor with an IC50 of 0.002 µM. IRAK4-IN-15 shows good human PK predictions with low intrinsic clearance. IRAK4-IN-15 shows great synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL in combination with Acalabrutinib. .

Product Details

Target	IRAK
Molecular Weight	488.56
SMILES	CC1=NC=C(C2=NC3=C(NC(C)C)N=C(NC4=CN(C(C5)CC65CN(C)C6)N=C4)N=C3C=C2F)C=N1

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.