IRAK4-IN-18

Cat. No.: IBDI-435882

IRAK4-IN-18 is a potent interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 value of 15 nM. IRAK4-IN-18 can inhibit LPS-induced IL23 production in THP and DC cells, and stop arthritis development in arthritis rats. IRAK4-IN-18 can be used for researching arthritis disease.

Product Details

Target	IRAK
Molecular Weight	464.49
SMILES	O=C(N)[[email protected]@H]1C([[email protected]@H]2C[[email protected]]1C=C2)NC3=NC(NC4=CC(N5CCOCC5)=CC(F)=C4)=NC6=C3OC=C6

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.