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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

IRE1α kinase-IN-2

Cat. No.: IBDI-434554

IRE1α kinase-IN-2 is a potent IRE1α kinase inhibitor, with an EC50 of 0.82 μM. IRE1α kinase-IN-2 inhibits IRE1α kinase autophosphorylation (IC50=3.12 μM). IRE1α kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines.

Size (Solid):

Product Details

Target IRE1
Molecular Weight 504.51
Appearance Solid
SMILES NC1=NC=CN2C1=C(C(C3=C4C=CC=C3)=CC=C4NC(NC5=CC(C(F)(F)F)=CC=C5)=O)N=C2C(C)C
Purity 98.50%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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