IRF7 Monoclonal Antibody

Target Information

Target Name	IRF7
Uniprot ID	Q92985
Cellular Localization	Nucleus. Cytoplasm. The phosphorylated and active form accumulates selectively in the nucleus.
Immunogen	Recombinant fragment.
Function	Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) in IFN promoters and in the Q promoter (Qp) of EBV nuclear antigen 1 (EBNA1). Functions as a molecular switch for antiviral activity. Activated by phosphorylation in response to infection. Activation leads to nuclear retention, DNA binding, and derepression of transactivation ability.

Product Details

Description	Rabbit monoclonal antibody to IRF7.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment.
Positive Control	WB: Jurkat treated with 100 nM IFN alpha for 18 hours, then added 10 µM MG-132 for another 6 hours, whole cell lysate. IP: Jurkat treated with 100 nM IFN alpha for 18 hours, then added 10 µM MG-132 for another 6 hours, whole cell lysate.
Application	IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.