Cat. No.: IBDA-431623
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Online InquiryTarget Information
| Target Name | IRF7 |
| Uniprot ID | Q92985 |
| Cellular Localization | Nucleus. Cytoplasm. The phosphorylated and active form accumulates selectively in the nucleus. |
| Immunogen | Recombinant fragment. |
| Function | Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) in IFN promoters and in the Q promoter (Qp) of EBV nuclear antigen 1 (EBNA1). Functions as a molecular switch for antiviral activity. Activated by phosphorylation in response to infection. Activation leads to nuclear retention, DNA binding, and derepression of transactivation ability. |
Product Details
| Description | Rabbit monoclonal antibody to IRF7. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse |
| Immunogen | Recombinant fragment. |
| Positive Control | WB: A20 treated with 10 ng/ml mouse IFN alpha for 24 hours, added 10 µM MG-132 for 6 hours, whole cell lysate |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |