IRF7 Polyclonal Antibody

Target Information

Target Name	IRF7
Uniprot ID	Q92985
Cellular Localization	Nucleus. Cytoplasm. The phosphorylated and active form accumulates selectively in the nucleus.
Immunogen	Synthetic peptide conjugated to KLH, corresponding to 14 amino acids near the center of Human IRF7.
Function	Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) in IFN promoters and in the Q promoter (Qp) of EBV nuclear antigen 1 (EBNA1). Functions as a molecular switch for antiviral activity. Activated by phosphorylation in response to infection. Activation leads to nuclear retention, DNA binding, and derepression of transactivation ability.

Product Details

Description	Rabbit polyclonal antibody to IRF7.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide conjugated to KLH, corresponding to 14 amino acids near the center of Human IRF7.
Positive Control	Human Spleen tissue
Application	IHC-P

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.4 Preservative: 0.02% Sodium Azide Constituent: 99% PBS
Handling	Avoid freeze-thaw cycles.