JAK3-IN-13

Cat. No.: IBDI-432449

JAK3-IN-13 is a potent, selective and orally active JAK3 inhibitor with IC50 values of 4728, 2039, 8, 365 nM for NK1, JNK2, JNK3, Tyk2, respectively. JAK3-IN-13 shows antiproliferative activity. JAK3-IN-13 induces cell cycle arrest at G0/G1 phase. JAK3-IN-13 shows antitumor activity.

Product Details

Target	JNK
Molecular Weight	533.02
SMILES	C=CC(NC1=CC(NC2=NC=C(Cl)C(O[[email protected]]3[[email protected]](OC[[email protected]]4OC)([H])[[email protected]]4([H])OC3)=N2)=CC=C1N(CCN(C)C)C)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.