JH-XIV-68-3

Cat. No.: IBDI-434045

JH-XIV-68-3 is a selective macrocyclic inhibitor of DYRK1A/B. JH-XIV-68-3 displays selectivity for DYRK1A and close family member DYRK1B in biochemical and cellular assays. JH-XIV-68-3 demonstrates antitumor efficacy in head and neck squamous cell carcinoma (HNSCC) cell lines.

Product Details

Target	DYRK
Molecular Weight	468.43
SMILES	FC(F)(F)C1=NN2C=C1C3=CNC4=NC=C(C=C43)C5=C(C#N)N(C)N=C5CN(C)C(CCC2)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.