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JHU-083

Cat. No.: IBDI-436873

JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals.

Size (Solid):

Product Details

Target GLUT | aminase
Molecular Weight 312.36
Appearance Solid
SMILES O=C(OCC)[[email protected]](CCC(C=[N+]=[N-])=O)NC([[email protected]](CC(C)C)N)=O
Purity ≥98.0%

Storage & Handling

Shipping Shipping with dry ice.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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