JMX0293

Cat. No.: IBDI-432531

JMX0293 is an O-alkylamino-tethered salicylamide derivative compound. JMX0293 maintains good potency against MDA-MB-231 cell line (IC50 = 3.38 μM) while exhibiting very low toxicity against human non-tumorigenic breast epithelial cell line MCF-10A (IC50> 60 μM). JMX0293 inhibits STAT3 phosphorylation and contribute to apoptosis in TNBC MDA-MB-231 cells. JMX0293 significantly suppresses MDA-MB-231 xenograft tumor growth in vivo without significant toxicity.

Product Details

Target	Apoptosis
Molecular Weight	569.43
SMILES	CC([[email protected]](NC(C1=C(C=CC(Cl)=C1)OCCNC(OC(C)(C)C)=O)=O)C(NC2=C(C=C(C=C2)[N+]([O-])=O)Cl)=O)C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.