JNJ-10198409
Cat. No.: IBDI-433915
JNJ-10198409 is a relatively selective, orally active, and ATP competitive PDGF-RTK (platelet-derived growth factor receptor tyrosine kinase) inhibitor (IC50=2 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM).
Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution
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Product Details
| Target |
PDGFR |
| Molecular Weight |
325.34 |
| Appearance |
Solid |
| SMILES |
COC1=CC2=C(C=C1OC)CC3=C2NN=C3NC4=CC=CC(F)=C4 |
| Purity |
98.79% |
Storage & Handling
| Shipping |
Room temperature in continental US. May vary elsewhere. |
| Storage |
Powder: -20°C/3 years
In solvent: -80°C/6 months; -20°C/1 month |
| Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.
