JNK3 inhibitor-5

Cat. No.: IBDI-434429

JNK3 inhibitor-5 (Compound 22b) is a potent and selective JNK3 inhibitor with an IC50 of 0.379 nM. JNK3 inhibitor-5 effectively protects the neuronal cells against amyloid beta-induced apoptosis. JNK3 inhibitor-5 has a high cell permeability and is predicted as BBB permeable.

Product Details

Target	JNK | Apoptosis | GSK-3 | p38 MAPK
Molecular Weight	540.44
SMILES	NC(C1CC2=C(C1)N=C(C3=CC(Cl)=C(C=C3)Cl)N2C4=NC(N[[email protected]@H]5CN(CCC5)C(C6CC6)=O)=NC=C4)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.