K145

Cat. No.: IBDI-435877

K145 is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM. K145 is inactive against SphK1 and other protein kinases. K145 induces cell apoptosis and has potently antitumor activity.

Product Details

Target	SphK | Apoptosis
Molecular Weight	348.46
SMILES	O=C(N(CCN)C/1=O)SC1=C/CCC2=CC=C(OCCCC)C=C2

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.