KDOAM-25 trihydrochloride

Cat. No.: IBDI-434424

KDOAM-25 trihydrochloride is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. KDOAM-25 trihydrochloride increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells.

Product Details

Target	Histone Demethylase
Molecular Weight	416.77
SMILES	NC(C1=CC=NC(CNCC(N(CC)CCN(C)C)=O)=C1)=O.Cl.Cl.Cl

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.