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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

KG-548

Cat. No.: IBDI-434004

KG-548 is an ARNT/TACC3 disruptor and a HIF-1α inhibitor. KG-548 directly interferes with ARNT/TACC3 complex formation by competing with TACC3 for binding to the ARNT PAS-B domain. ARNT is the aryl hydrocarbon receptor nuclear translocator, also known as HIF-β.

Size (Solid):

Product Details

Target HIF/HIF Prolyl-Hydroxylase
Molecular Weight 282.15
Appearance Solid
SMILES FC(C1=CC(C(F)(F)F)=CC(C2=NN=NN2)=C1)(F)F
Purity ≥98.0%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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