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KIRA9

Cat. No.: IBDI-437772

KIRA9 is a potent IRE1 inhibitor (IC50=4.8 μM in INS-1 cells). KIRA9 is able to fully engage the ATP-binding site of IRE1α. KIRA9 can block ER-localized mRNA decay and apoptosis.

Size (Solid):

Product Details

Target IRE1 | Apoptosis
Molecular Weight 572.60
SMILES O=S(NC1=CC=C(OC2=NC=CC=C2C3=CC=NC(N[[email protected]@H]4CNCCC4)=N3)C5=C1C=CC=C5)(CCC(F)(F)F)=O

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.