KRAS G12C inhibitor 43

Cat. No.: IBDI-432436

KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively.

Product Details

Target	Ras
Molecular Weight	577.68
SMILES	C=CC(N1CCN(C[[email protected]@H]1CC#N)C2=C3C=CC(C4=C5C=CC=CC5=CC(OC)=C4)=NC3=NC(OC[[email protected]@H]6CCCN6C)=N2)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.