KRAS inhibitor-17

Cat. No.: IBDI-432441

KRAS inhibitor-17 (compound 3-9) is a potent KRAS G12C inhibitor with an IC50 of 3.37 µM. KRAS inhibitor-17 shows p-ERK inhibition activities with IC50s of 9.25, >33.3 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-17 has the potential for the research of pancreatic, colorectal, and lung cancers.

Product Details

Target	Ras
Molecular Weight	466.36
SMILES	C=CC(N1CCN(CC1)C2=C3C=C(C(C4=CC(OC)=CC=C4Cl)=C(C3=NS2)F)Cl)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.