L-Buthionine-(S,R)-sulfoximine

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L-Buthionine-(S,R)-sulfoximine

Cat. No.: IBDI-434327

L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.

Size (Solution): 10 mM * 1 mL in Water

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Ferroptosis
Molecular Weight	222.31
Appearance	Solid
Synonyms	L-Buthionine sulfoximine, L-BSO
SMILES	N[[email protected]](C(O)=O)CCS(CCCC)(=O)=N
Purity	≥98.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.