L-SepIAP; terin

Cat. No.: IBDI-430031

L-SepIAP; terin (SepIAP; terin) is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-SepIAP; terin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. L-SepIAP; terin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70 S6K-dependent VEGFR-2 expression.

Product Details

Target	Endogenous Metabolite
Molecular Weight	237.22
Appearance	Solid
Synonyms	SepIAP, terin
SMILES	O=C1NC(N)=NC2=C1N=C(C([[email protected]@H](O)C)=O)CN2
Structure Classification	Alkaloids

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.