Levocabastine hydrochloride

Cat. No.: IBDI-437813

Levocabastine (R 50547) hydrochloride is a potent and selective histamine H1-receptor antagonist. Levocabastine hydrochloride is also a selective, high affinity neurotensin receptor subtype 2 (NTR2) antagonist, with a Ki of 17 nM for mNTR2. Levocabastine hydrochloride can act as a VLA-4 antagonist, interferes with conjunctival eosinophil infiltration in allergic conjunctivitis (AC).

Product Details

Target	Histamine Receptor | Neurotensin Receptor | Integrin
Molecular Weight	456.98
Appearance	Solid
Synonyms	R 50547 hydrochloride
SMILES	OC([[email protected]@]1(C2=CC=CC=C2)[[email protected]@H](CN([[email protected]]3([H])CC[[email protected]](CC3)(C4=CC=C(C=C4)F)C#N)CC1)C)=O.[H]Cl
Purity	≥99.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.