Linrodostat

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Cat. No.: IBDI-436290

Linrodostat (BMS-986205) is a selective and irreversible indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 value of 1.1 nM in IDO1-HEK293 cells. Linrodostat is well tolerated with potent pharmacodynamic activity in advanced cancers.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Indoleamine 2,3-Dioxygenase (IDO)
Molecular Weight	410.91
Appearance	Solid
Synonyms	BMS-986205, ONO-7701
SMILES	O=C(NC1=CC=C(Cl)C=C1)[[email protected]](C)[[email protected]@](CC2)([H])CC[[email protected]]2C3=CC=NC4=C3C=C(F)C=C4
Purity	99.89%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.