Lipoxin A4-d5

Cat. No.: IBDI-431459

Lipoxin A4-d5 is the deuterium labeled Lipoxin A4. Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM.

Product Details

Target	Interleukin Related | Endogenous Metabolite
Molecular Weight	357.50
Synonyms	LXA4-d5
SMILES	O[[email protected]](/C=C/C=C\C=C\C=C\[[email protected]]([[email protected]](CCCC(O)=O)O)O)CCCC([2H])(C([2H])([2H])[2H])[2H]

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.